Editing Non-Urothelial Bladder Cancer

== Small cell carcinoma of the bladder ==

* '''Type of neuroendocrine histology'''
* '''Should be considered and treated as metastatic disease, even if there is no radiologic evidence of disease outside the bladder'''
* In general, primary small cell carcinoma of the bladder is '''very chemosensitive'''
* '''Primary mode of therapy is chemoradiation therapy; chemotherapy and radical cystectomy is an option with similar survival''' (5-year CSS 16% chemoradiation vs. 18% chemotherapy and radical cystectomy)
* Primary method to improve survival will be more effective systemic therapy

== Signet ring cell carcinomas ==

* '''Usually high-grade, high-stage tumors at presentation'''
* '''Poor prognosis'''

== Sarcoma ==

* Subclassification of sarcoma is based on histologic variations, depending on the specific malignant cell type
* '''Leiomyosarcoma is the most common histologic subtype''', followed by rhabdomyosarcoma and then, rarely, angiosarcoma, osteosarcoma, and carcinosarcoma

== Questions ==

== Answers ==

== References ==

* Wein AJ, Kavoussi LR, Partin AW, Peters CA (eds): CAMPBELL-WALSH UROLOGY, ed 11. Philadelphia, Elsevier, 2015, chap 92