Editing Functional: Pathophysiology and Classification of LUT Dysfunction (section)

==== Bladder Underactivity ====

* May result from temporary or permanent failure or impairment in one of the neuromuscular mechanisms necessary for initiating and maintaining a normal detrusor contraction.
* '''<span style="color:#ff0000">Causes:</span>'''
** '''<span style="color:#ff0000">Neurologic diseases affecting the lumbosacral cord or conus medullaris.</span>'''
** '''<span style="color:#ff0000">Systemic diseases, which can result in peripheral neuropathies such as diabetes, tabes dorsalis, and alcoholism</span>'''
*** Whereas early in the disease process diabetes can lead to UUI, later in the process sensation can be altered as can detrusor contractility, resulting in impaired bladder emptying, UTIs, and UI.
** '''<span style="color:#ff0000">Radical pelvic surgeries''' (i.e., radical hysterectomy, abdominoperineal resection)</span>