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== Fibromuscular Dysplasia (FMD) == * '''More often seen in younger Caucasian women''' * '''Usually bilateral''' [think two-clip] * Most common presenting symptoms: hypertension, headache, and pulsatile tinnitus * '''Subtypes (4):''' *# '''Multifocal''' *## '''Medial fibroplasia''' *# '''Focal''' *## '''Perimedial fibroplasia''' *## '''Intimal fibroplasia''' *## '''Medial hyperplasia''' ** '''Multifocal''' *** '''Medial fibroplasia''' **** '''Most common type of FMD (70-80%)''' **** Occurs almost exclusively in women between age 25-50 **** '''Lesions involve the distal half of the main renal artery''' and may extend into the branches **** '''Unlikely to progress to complete occlusion or loss of renal function''' ** Insert figure ** '''Focal''' *** '''Intimal fibroplasia''' **** '''Most common type of focal FMD'''Β§ **** '''May result in dissection, arterial wall hematoma, and renal infarction''' **** '''Likely to progress to loss of renal function without intervention''' **** '''See Figure 117-4''' ***** '''Renal arteriogram demonstrates a localized, highly stenotic, smooth lesion involving the distal renal artery, from intimal fibroplasia''' *** '''Perimedial fibroplasia''' **** 10-25% of FMD cases **** Occurs almost exclusively in women but they are younger (age 5-15) than medial fibroplasia **** '''The stenosis occurs classically in the midrenal artery''' **** '''Likely to progress to loss of renal function without intervention''' *** '''Medial hyperplasia''' **** Rare **** '''Likely to progress to loss of renal function without intervention''' * Duplex Doppler ultrasound surveillance of kidney length and cortical thickness should be done once or twice a year.
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