Editing Adrenal: Hyperaldosteronism (section)

== Answers ==

# What is the most potent stimulator of aldosterone secretion? What are other stimulators of aldosterone secretion?
#* Angiotensin II
#* ACTH and elevated serum potassium
# What is the categorization of causes of hyperaldosteronism? What lab test can be used to differentiate them?
#* Primary vs. secondary
#* Plasma aldosterone-renin ratio
# List 8 causes of primary hyperaldosteronism
## Bilateral hyperplasia
## Aldosterone-producing adrenal adenoma
## Unilateral adrenal hyperplasia
## Aldosterone-producing ACC
## Ectopic aldosterone-producing tumour
## Familial hyperaldosteronism I
## Familial hyperaldosteronism II
## Familial hyperaldosteronism III
# List 9 indications for primary aldosteronism screening?
# Which medications should be held prior to testing for hyperaldosteronism?
# What are the surgically correctable subtypes of hyperaldosteronism? What are the non correctable by surgery subtypes of hyperaldosteronism?
#* Surgically correctable: aldosterone-producing adrenal adenoma, unilateral adrenal hyperplasia, ectopic aldosterone-secreting tumor, aldosterone-producing adrenal cortical carcinoma
#* Not correctable by surgery: bilateral adrenal hyperplasia, familial hyperaldosteronism type I, familial hyperaldosteronism type II, familial hyperaldosteronism type III
# What laboratory test do the CUA guidelines recommend to rule out primary hyperaldosteronism?
# How is laterality of primary hyperaldosteronism established? When should this not be performed?
#* Adrenal vein sampling; lateralization cannot be established on imaging alone
#* Patients <40 years with a clear unilateral adrenal adenoma and normal contralateral adrenal gland on imaging or patients suspected of having an ACC
# What are medical treatments for the non correctable by surgery subtypes of hyperaldosteronism?
#* Mineralocorticoid receptor antagonists such as spironolactone and eplerenone