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Pediatrics: Renal and Adrenal Oncology
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=== Staging === {| class="wikitable" |'''Stage''' |'''Description''' |- |'''1''' | * Localized tumor * Complete gross excision * Ipsilateral lymph nodes involvement negative under microscopic examination |- |'''2A''' | * Localized tumor * '''Incomplete gross resection''' * Ipsilateral lymph nodes involvement negative under microscopic examination |- |'''2B''' | * Localized tumor * Complete or incomplete gross resection * '''Ipsilateral lymph nodes involvement positive under microscopic examination''' * Enlarged contralateral lymph nodes but with negative involvement under microscopic examination |- |'''3''' | * '''Localized unilateral tumor with contralateral lymph nodes involvement positive under microscopic examination''' <center>'''or'''</center> * '''<span style="color:#ff0000">Unresectable unilateral tumor</span> infiltrating across the midline''' with positive or negative regional lymph node involvement <center>'''or'''</center> * Unresectable midline tumor with bilateral infiltration or lymph node involvement |- |'''4''' | * '''<span style="color:#ff0000">Metastasis of the tumor to distant lymph nodes''' * '''<span style="color:#ff0000">Metastasis of the tumor to liver, skin, organs (except as defined by Stage 4S)''' |- |'''4S''' | * '''Limited to infants <1 year of age''' * '''Localized primary tumor (as defined for stage 1, 2A, or 2B)''' * '''Metastasis of the tumor limited to skin, liver and/or bone marrow''' * '''Bone marrow involvement in stage 4S should be minimal''' (<10% of total nucleated cells identified as malignant on bone marrow biopsy) |}
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