Editing Sexually Transmitted Infections (section)

===== Chancroid =====
* '''Caused by H. ducreyi (gram-negative coccobacilli)'''
* '''Initial presentation of a papule that may progress to anogenital painful ulceration and lymphadenitis with progression to bubo formation'''
* '''Incubation period: 3-10 days'''
* Most common site of infection: prepuce
* '''Diagnosis and Evaluation'''
** '''Labs'''
*** '''Definitive diagnosis requires culture on media not routinely available.'''
*** '''Centers for Disease Control and Prevention suggests that a probable diagnosis of chancroid can be made if''':
***# The patient has one or more painful ulcers
***# No evidence of T. pallidum is present on darkfield examination of ulcers or by serologic testing for syphilis performed at least 7 days after onset of the ulcers
***# Ulcers and lymphadenopathy, if present, are typical for chancroid
***# Results of tests for HSV on the ulcer exudate are negative
*** Chancroid, like genital herpes and syphilis, is a risk factor for transmission of HIV; patients should be tested for HIV at the time of diagnosis of chancroid
* '''Management'''
** '''Options:'''
**# '''Azithromycin 1g in a single dose or'''
**# '''Ceftriaxone 250 mg IM in single dose''' or
**# Ciprofloxacin 500 mg orally BID x 3 days or
**# Erythromycin base 500 mg orally TID x 7 days