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Functional: Nocturia
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=== Management === *'''Directed at underlying cause''' ** '''Phytotherapies''' *** '''Pygeum africanum and cernilton are associated with improvement in nocturia''' ** '''Medical therapy''' *** Ξ±-blockers, 5-ARIs, antimuscarinics, and antimuscarinics plus Ξ±-blockers have occasionally been found to have a statistically significant reduction in nocturia episodes, but clinical significance appears to be minimal. *** '''When 5-ARIs and Ξ±-blockers are used in combination, they have the same degree of success as Ξ±-blockers alone''' *** '''The optimal patients to treat with medications that target the bladder and the prostate appear to be those who have a large number of nocturia episodes (mostly resulting from severe urgency)''' ** '''Surgery''' *** Patients with '''high-pressure urinary retention''' causing nocturnal enuresis are treated by initial catheterization to relieve the pressure, followed by appropriate assessment with a view to using endoscopic surgery to resect, vaporize, or enucleate the prostate, or open removal of the prostate **** '''Treating bladder outlet obstruction is thought to improve nocturia''' by: ***** Lowering postvoid residual volume ***** Increasing functional bladder capacity ***** Reducing urinary frequency **** '''TURP appears to be superior to tamsulosin for treatment of BPH-related nocturia'''
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