Editing AUA: Early Detection of Prostate Cancer (2023) (section)

=== Approach ===

*'''<span style="color:#ff0000">Transrectal or transperineal biopsy route may be used when performing a biopsy.</span>'''
** '''Cancer detection rates associated with transrectal versus transperineal biopsy route are not significantly different.'''
**Advantages of transperineal approach
***May detect anterior and apical cancers at a higher rate
****Prospective, randomized data are lacking and existing data are contradictory.
***Lower risk of infection 
****Prospective, randomized data are lacking to make a definitive conclusion.
** Advantages of transrectal approach 
***Patient preference/comfort
***Patient cannot be placed into the lithotomy position
***Clinician training/experience or lack of appropriate equipment for the transperineal approach.
**'''<span style="color:#ff0000">Transperineal biopsies may have some value in patients (3):</span>'''
**#'''<span style="color:#ff0000">Infectious complications with a prior biopsy</span>'''
**#'''<span style="color:#ff0000">Higher risk for biopsy-related infection</span>'''
**#'''<span style="color:#ff0000">Anterior lesions that may not be as easily accessible transrectally</span>'''