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Functional: Neural Control of Storage and Voiding
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=== Voiding reflexes === * See [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897743/figure/F5/ Figure 5b] for voiding reflex * '''Also known as “micturition reflex”, “spinobulbospinal reflex”''' * '''<span style="color:#ff0000">Upon initiation of micturition, there is high-level afferent activity signaling wall tension, which activates the PMC</span>''' * '''<span style="color:#ff0000">In response, the PMC:</span>''' *# '''<span style="color:#ff0000">Inhibits the guarding reflex, thereby reducing sympathetic</span>''' (resulting in inhibition (relaxation) of bladder base and urethra and excitation (contraction) of the detrusor muscle) '''<span style="color:#ff0000">and pudendal</span>''' (resulting in inhibition (relaxation) of EUS) '''<span style="color:#ff0000">nerve outflow</span>''' *# '''<span style="color:#ff0000">Stimulates parasympathetic outflow resulting in (2):</span>''' *## '''<span style="color:#ff0000">Excitation (contraction) of bladder</span>''' *## '''<span style="color:#ff0000">Inhibition (relaxation) of [urethra]/</span>'''internal sphincter smooth muscle * '''Maintenance of the voiding reflex is through ascending afferent input from the spinal cord, which may pass through the periaqueductal gray matter (PAG) before reaching the PMC''' * Described as a spinobulbospinal reflex because of the ascending signal from afferent pelvic nerve stimulation, which passes through the periaqueductal gray matter in the bulbar region of the brain before reaching the pontine micturition center and descending to elicit parasympathetic contraction of the detrusor, and somatic relaxation via the pudendal nerve
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