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Neurogenic LUT Dysfunction
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==== Vesicoureteral reflux ==== * '''Incidence between 17-25% in SCI patients, more common in those with suprasacral SCI.''' ** Persistent reflux can lead to chronic renal damage and may be an important factor in the long-term survival of SCI patients. * '''Contributing factors include:''' *# '''Elevated intravesical pressure during filling and emptying''' *# '''Infection''' * '''Management''' ** '''The best initial treatment for VUR in a patient with voiding dysfunction secondary to neurologic disease or injury is to normalize LUT urodynamics (i.e., decrease storage pressures and decrease outlet resistance) as much and as quickly as possible.''' *** Depending on the clinical circumstances, this may be achieved by pharmacotherapy, urethral dilatation (in the myelomeningocele patient), neuromodulation, deafferentation, augmentation cystoplasty, or sphincterotomy
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