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Pathophysiology of Urinary Tract Obstruction
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== Clinical impact of renal obstruction == * '''Hypertension''' ** '''More common in the presence of BUO than UUO.''' ** '''More likely to be reversed after relief of BUO than UUO''' * '''Compensatory renal growth in response to UUO or renal agenesis''' ** The development of contralateral renal growth is influenced by age and the degree and duration of obstruction. This adaptive response allows the remaining kidney to ensure homeostasis and compensate for the lack of functioning contralateral renal tissue ** The increase in renal volume related to compensatory renal growth is '''primarily a consequence of cellular hypertrophy rather than hyperplasia'''
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