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Germ Cell Tumours
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==== Physical exam ==== * '''Genitourinary''' ** Palpate for any testicular or extra-testicular masses. Note relative size and consistency of affected and normal contralateral testicle. ***'''A firm intratesticular mass should be managed as a malignant neoplasm until proven otherwise and should be evaluated further with a scrotal ultrasound scan.''' ** '''<span style="color:#ff0000">Differential diagnosis of a scrotal mass (8):</span>''' **# '''<span style="color:#ff0000">Painless</span>''' **##'''<span style="color:#ff0000">Testicular neoplasm</span>''' **##'''<span style="color:#ff0000">Paratesticular neoplasm (benign or malignant)</span>''' **## '''<span style="color:#ff0000">Hernia</span>''' **## '''<span style="color:#ff0000">Varicocele</span>''' **## '''<span style="color:#ff0000">Spermatocele</span>''' **#'''<span style="color:#ff0000">Painful</span>''' **##'''<span style="color:#ff0000">Torsion</span>''' **## '''<span style="color:#ff0000">Hematoma</span>''' **## '''<span style="color:#ff0000">Epididymoorchitis</span>''' * '''Sites of metastases''' ** '''Supraclavicular lymph nodes''' ** Inguinal lymph nodes, if prior inguinal or scrotal surgery * '''Gynecomastia''' ** '''Occurs in 2% of males with GCT''' ** Results from elevated serum hCG levels, decreased androgen production, and/or increased estrogen levels
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