Editing Penile Cancer: Squamous Penile Cancer (section)

=== CIS ===

* '''<span style="color:#ff0000">Non-surgical</span>'''
** '''<span style="color:#ff0000">Topical</span>'''
*** '''EAU: Circumcision is advisable prior to the use of topical agents'''
*** '''<span style="color:#ff0000">Options (2):</span>'''
***# '''<span style="color:#ff0000">5-fluorouracil cream (5% concentration BID x 6 weeks)</span>'''
***# '''<span style="color:#ff0000">Imiquimod 5% cream</span>'''
*** '''Patient adherence and strict follow-up is a must, and prompt re-biopsy is necessary for lesions that fail to respond'''
*** '''If topical treatment fails, it should not be repeated.'''
** '''<span style="color:#ff0000">Ablation with lasers</span>'''
*** '''Two commonly used laser mediums are''' '''carbon dioxide (CO2''') '''and Nd:YAG;''' conflicting literature regarding their efficacy for cancerous lesions
* '''<span style="color:#ff0000">Surgical</span>'''
** '''Foreskin lesion'''
*** '''Circumcision or excision with a 5-mm margin is adequate'''
** '''Glans lesion'''
*** '''Excisional strategies while maintaining normal penile anatomy'''
* '''<span style="color:#ff0000">Radiation</span>'''
** '''Can be used for tumours that are resistant to topical treatment, especially among patients who are not surgical candidates'''
* '''<span style="color:#ff0000">Moh's surgery</span>'''