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AUA: Male Urethral Stricture (2016)
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==Risk Factors== *'''Trauma History Increases Loo Time (5):''' #'''<span style="color:#ff0000">Trauma</span>''' #'''<span style="color:#ff0000">Hypospadias surgery</span>''' #'''<span style="color:#ff0000">Instrumentation or urethral catheterization</span>''' #'''<span style="color:#ff0000">Lichen sclerosus (LS)</span>''' # '''<span style="color:#ff0000">Transurethral surgery</span>'''*'''Most common cause''' **'''In developed countries: idiopathic (41%) followed by iatrogenic (35%),''' with transurethral surgery as the most common iatrogenic cause. **'''In developing countries: trauma''' (36%) *'''Strictures related to hypospadias and lichen sclerosus are generally located in the penile urethra, while traumatic strictures and stenoses tend to be located in the bulbar and posterior urethra''' * '''LS-related strictures'''**Less common etiology **'''Tend to be longer and may have a higher association with urethral cancer'''***'''For suspected LS, biopsy may be performed; if urethral cancer is suspected, biopsy must be performed''' ****The rate of squamous cell carcinoma in male patients with LS has been reported to be 2-9% thus further indicating the need for biopsy in selected cases both to confirm the diagnosis as well as to exclude malignant or premalignant changes.
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