Editing Adjuvant and Salvage Radiotherapy After Prostatectomy (2019) (section)

== Advantages vs. Disadvantages ==

* '''ART'''
**'''Disadvantage'''
*** '''Overtreatment with ART:''' ART may involve irradiation of some patients who never would have had recurrent cancer, thus exposing them unnecessarily to the risks, toxicity, and QoL impact of RT. SRT avoids overtreatment.
* '''SRT'''
**'''Disadvantage'''
***'''Delayed treatment with SRT:''' waiting to administer RT as a salvage therapy could be less effective, particularly in patients with high-risk disease, and could allow the progression to metastatic disease.
* '''At the time of guideline publication, no published trials comparing ART vs. SRT'''
**Observational studies suggest that ART patients generally have better outcomes compared to SRT patients. However, this is difficult to compare these groups that SRT studies focus only on patients who have already relapsed and the ART group has patients that were never destined to recur