Editing Biochemical Recurrence (section)

=== Background ===

* '''After successful radical prostatectomy (complete removal of prostate and cancer), PSA is expected to become undetectable''' (after the appropriate number of half-lives for elimination; recall PSA half-life 2-3 days and fraction remaining is 1/(2exp(n)) where n is number of half-lives)
*'''<span style="color:#ff0000">Detectable and rising PSA is usually the earliest evidence of tumor recurrence after radical prostatectomy</span>'''
** '''This rising PSA normally precedes clinically meaningful events in an extremely protracted and variable manner.''' (see Pound et al. below)