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Penile Cancer: Squamous Penile Cancer
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== Risk factors == # '''<span style="color:#ff0000">Lack of circumcision</span>''' #* '''<span style="color:#ff0000">Neonatal circumcision</span>''' #** '''<span style="color:#ff0000">Almost eliminates risk of invasive penile cancer</span>''' #*** The controversial discussion about neonatal circumcision should take into account that circumcision removes approximately half the tissue that can develop into penile cancer #** '''Does not demonstrate the same level of protection for CIS''' #* '''<span style="color:#ff0000">Adult circumcision</span>''' #** '''<span style="color:#ff0000">Offers little to no protection</span>''' # '''<span style="color:#ff0000">HPV (subtype 16 most frequently; oncologic subtypes: 16 and 18, non-oncologic subtypes: 6 and 11)</span>''' #'''<span style="color:#ff0000">Phimosis</span>''' # '''<span style="color:#ff0000">Lichen sclerosus, chronic penile inflammation</span>''' # '''<span style="color:#ff0000">Tobacco exposure (smoking, chewing tobacco)</span>''' # '''<span style="color:#ff0000">Poor hygiene, rural areas, low socioeconomic status, unmarried</span>''' # '''<span style="color:#ff0000">Number of sexual partners, early age of sexual intercourse</span>''' # '''<span style="color:#ff0000">Penile trauma</span>''' # '''<span style="color:#ff0000">Sporalene and ultraviolet A phototherapy (PUVA) for various dermatological conditions such as psoriasis</span>''' #* PUVA is a combination treatment which consists of Psoralens (P) and then exposing the skin to UVA (long wave ultraviolet radiation)
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