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== Gross Structure == * Ovoid in shape * '''The base of the prostate is at the bladder-prostate junction''' * The narrowed '''apex is the most inferior portion of the prostate gland,''' reaching the urogenital diaphragm. '''The apex of the prostate is continuous with the striated urethral sphincter''' * '''The prostate is fixed to the pubic bone anteriorly by the puboprostatic ligaments near the apex of the prostate''' * '''Composed of (2):''' **'''Fibromuscular stroma''' **'''Glandular elements''' === Fibromuscular stroma === * '''≈30% of the prostate's composition''' * Non-glandular component * Continuous with the detrusor fibres of the bladder neck and tapers distally toward the striated sphincter area[https://www.baus.org.uk/_userfiles/pages/files/Publications/Transrectal%20Ultrasound%20%20Prostatic%20Biopsy%20FINAL.pdf] *Tightly adherent to the glandular tissue of the prostate[https://www.baus.org.uk/_userfiles/pages/files/Publications/Transrectal%20Ultrasound%20%20Prostatic%20Biopsy%20FINAL.pdf] **Not described as a seperate entitiy on US === Glandular elements === * '''≈70% of the prostate's composition'''[[File:Prostate zones.png|alt=Prostate Anatomy Zones|thumb|710x710px|Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: NoneMikael Häggström, M.D., CC0, via [[commons:File:Prostate_zones.png|Wikimedia]] Commons]] * '''<span style="color:#ff0000">Divided into anatomic zones (largest to smallest) (3):</span>''' *# '''<span style="color:#ff0000">Peripheral zone</span>''' *#* '''≈70% of the glandular prostate tissue''' *#* '''<span style="color:#ff0000">Most (≈70%) prostate cancers occur in the peripheral zone</span>''' *# '''<span style="color:#ff0000">Central zone</span>''' *#* '''≈25% of the glandular prostate tissue''' *#* '''<span style="color:#ff0000">Surrounds the opening of the ejaculatory ducts</span>''' *# '''<span style="color:#ff0000">Transitional zone</span>''' *#* '''≈3-5% of the glandular prostate tissue''' *#*In the young adult male, only constitutes about 5-10% of male prostate; with age and the development of BPH, the TZ can occupy a large part of the glandular prostate[https://www.baus.org.uk/_userfiles/pages/files/Publications/Transrectal%20Ultrasound%20%20Prostatic%20Biopsy%20FINAL.pdf] *#*Anterior to the peripheral zone *#* '''Separated''' </span>'''from the rest of the glandular compartments of the prostate by a distinct fibromuscular band</span>''' *#* '''<span style="color:#ff0000">Benign prostatic hyperplasia most commonly occurs in the transitional zone</span>''' *#* '''<span style="color:#ff0000">≈20% of prostate cancers occur in the transitional zone</span>'''
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