Editing Urothelial Cancer of the Prostate (section)

== Pathophysiology ==

* Most patients with urothelial carcinoma of the prostatic ducts and acini will have direct extension of the bladder cancer into the prostatic urethra; however, some patients will have pagetoid spread underneath normal-appearing urothelium at the bladder neck
** Intraductal and infiltrating urothelial carcinoma involving the prostate tends to be seen in higher-stage bladder tumors

* '''Risk factors for prostatic urethral involvement include (5):'''
*# '''Presence of bladder CIS'''
*# '''Previous intravesical chemotherapy'''
*# '''Multi-focal disease'''
*# '''Tumours at the trigone or bladder neck'''
*# '''High-risk NMIBC'''