Editing Functional: Neural Control of Storage and Voiding (section)

== Storage phase ==

* '''The accommodation of the bladder to increasing volumes of urine is dependent on the intrinsic properties of the vesical smooth muscle and stroma, as well as the quiescence of the parasympathetic efferent pathway'''
* '''The bladder sympathetic reflex (guarding reflex) also contributes as a negative feedback or urine storage mechanism that promotes closure of the urethral outlet''' and inhibits neurally mediated contractions of the bladder during bladder filling
* '''However, the guarding reflex during urine storage may be weak in humans; in patients undergoing bilateral RPLND, in which the sympathetic chains are destroyed, there is no discernible alteration of filling or storage function'''