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Management of Localized and Locally Advanced Disease
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==== <span style="color:#ff0000">Indications</span> ==== * '''<span style="color:#ff0000">Alternative approach for management of cT1a solid renal masses <3cm</span>''' ** '''Current technology does not allow for reliable treatment of lesions >4.0 cm, and success rates appear to be highest for tumors <2.5-3.0 cm''' * '''Relative (4):''' *# '''Advanced age''' *# '''Significant comorbidities''' *# '''Local recurrence after previous nephron-sparing surgery''' *# '''Hereditary renal cancer who present with multifocal lesions for which multiple PNs might be cumbersome''' * '''<span style="color:#ff0000">2021 AUA[https://www.auanet.org/guidelines/renal-cancer-renal-mass-and-localized-renal-cancer-guideline]</span>''' ** '''<span style="color:#ff0000">Alternative approach for management of cT1a solid renal masses <3cm</span>''' *** Patients should be informed about the increased risk of tumor persistence or local recurrence after primary TA, compared to surgical excision, which may be treated with repeat ablation. ***PN seems preferred over TA for cT1a: "PN should be prioritized in the management of patients with clinical T1a renal mass".
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