Editing Penile Cancer: Squamous Penile Cancer (section)

=== Treatment of Primary Penile Tumour Summary ===
* Tis (glans): Laser therapy, glans resurfacing; alternative: topical therapy
* Ta, Tis (foreskin, shaft skin): Surgical excision to achieve negative margin; alternatives: laser therapy, topical therapy (Tis only)
* Ta, T1 grade 1-3
** Glans: Therapy based on size and position of lesion as well as potential side effects, excision, glans resurfacing procedures, glansectomy, radiotherapy (not indicated for Ta)
** Foreskin, shaft: Complete surgical excision to achieve negative margin
* T2 (glans) without gross cavernosum involvement: Total glansectomy with or without corpora cavernosa transection to achieve negative surgical margins, partial penectomy, radiotherapy
* T2 (corporeal invasion), T3: Partial or total penectomy
* '''T4 (adjacent structures): Consider neoadjuvant chemotherapy with surgical consolidation for responding patients if baseline resectability is a concern'''
* Local disease recurrence after conservative therapy: Complete surgical excision to achieve negative surgical margins; may require partial or total penectomy; select patients with superficial low-grade recurrences may be candidates for repeat penile-conserving procedure
* Radiotherapy: Select patients with T1-T2 tumors involving glans, coronal sulcus <4 cm