Editing CUA: Antenatal hydronephrosis (2017) (section)

==== Diuretic renography ====
* '''<span style="color:#ff0000">Nuclear tracer'''
**'''<span style="color:#ff0000">MAG3 diuretic renogram is test of choice for the assessment of the function of a hydronephrotic kidney'''
***Permits assessment of both the differential renal function (DRF) and the drainage time
*** Dimercaptosuccinic acid (DMSA) study can be considered to establish early split function in cases of neonates or premature infants, since the DRF in this study is not influenced by an immature GFR.
* '''<span style="color:#ff0000">Indications (1)'''
*# '''<span style="color:#ff0000">APD >15 mm or high-grade hydronephrosis (SFU 3-4) with VCUG was negative for VUR''' 
*#*'''To identify other potential causes of hydronephrosis (such as UPJO, UVJO)'''
**'''Not necessary in the evaluation of isolated LGHN (SFU 1‒2) with normal renal parenchyma and symmetric renal size'''
*Renogram should include a report of 
**Differential renal function, which can vary from 45‒55%
**Cortical transit time, which is normal up to 5 minutes
**Half-time
**Shape of the curve
* '''Test results can be influenced by'''
** '''Poor renal function (single kidney glomerular filtration rate [GFR] <15 ml/min)'''
** '''Poor hydration'''
** '''Massively dilated collecting system'''
** '''Full bladder'''
** '''Dilated distal ureter'''
* Renograms can be performed at any age, as long as they are used as a baseline study for serial comparison'''.'''