Editing Hormonal Therapy (section)

== Response to androgen blockage ==

* '''Following the initiation of ADT, the vast majority of prostate cancer patients will show some evidence of clinical response'''
* '''PSA response to ADT is associated with clinical outcomes; the magnitude and rapidity of that response remain the best predictors of its durability'''
** Assuming ADT effectively targets the androgen-sensitive population of prostate cancer cells, '''an incomplete or sluggish response is evidence of a significant androgen-refractory cell population'''