Editing Transurethral Resection of Bladder Tumour (section)

== Post-operative Instillation ==

* '''<span style="color:#ff0000">Consider post-operative instillation of intravesical chemotherapy, if appropriate</span>'''
**'''See [[CUA & AUA: Non-muscle Invasive Bladder Cancer (2021 CUA & 2020 AUA)|CUA & AUA: Non-muscle Invasive Bladder Cancer]] Guideline Notes'''
* '''<span style="color:#ff0000">Continuous bladder irrigation (CBI) may be of benefit</span> to reduce risk of recurrence based on floating tumour cells and implantation theory'''
** '''<span style="color:#ff00ff">Systematic review of CBI following TURBT for non-muscle invasive bladder cancer</span>'''
*** 6 studies meeting inclusion criteria
**** 2 studies (without peer-reviewed publication) compared CBI vs. no CBI and found that CBI reduced risk of at 2 years
**** 4 studies from 3 randomized trials compared CBI vs. intravesical chemotherapy and found similar recurrence rates at 1 year (odds ratio 1.29, 95% confidence interval 0.78-2.13) but a lower risk of adverse events (6-34% versus 27-48%)
*** [https://pubmed.ncbi.nlm.nih.gov/33890701/ Li, Mo, et al.] "Continuous bladder irrigation after transurethral resection of non‐muscle invasive bladder cancer for prevention of tumour recurrence: a systematic review." ''ANZ Journal of Surgery'' 91.12 (2021): 2592-2598.