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=== Complicated Cystitis in Females === * '''Complicated UTIs requires either (5):''' *# '''Anatomic or functional abnormality of urinary tract (outlet obstruction, stone disease, diverticulum, neurogenic bladder, VUR etc.)''' *# '''Urinary instrumentation or foreign bodies in the urinary tract (i.e. catheters, stents, nephrostomy tubes)''' *# '''Systemic disease (renal insufficiency, diabetes, immunodeficiency, organ transplantation)''' *# '''Pregnancy''' *# '''Multi–drug resistant bacteria''' * '''Diagnosis and Evaluation''' **'''Labs''' ***'''Urine cultures''' ****'''Mandatory to identify the bacteria and its antibiotic susceptibility''' ****Prior cultures should be reviewed and empiric selection of those results * '''Management''' ** '''Patients who are candidates for outpatient therapy:''' *** '''Oral ciprofloxacin 500 mg BID x 7 days''' *** Once daily oral fluoroquinolone (ciprofloxacin 1000 mg ER x 7 days or levofloxacin 750 mg x 5 days) *** Oral TMP-SMX DS BID x 14 days (not for Enterococcus or Pseudomonas)
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