Editing Disorders of Sexual Differentiation (section)

===== Mild Androgen Insensitivity Syndrome =====
* '''Variety of mutations, usually quite discrete within the androgen receptor gene, that accounts for the infertility in these patients'''
** This suggests that infertility in otherwise normal males may be the clinical manifestation of mild androgen insensitivity, representing the far end of a variable phenotypic spectrum.
* May have normal phenotypically or have a history of mild hypospadias repair but are azoospermic or severely oligospermic.
* '''Endocrine evaluation demonstrates normal to elevated serum testosterone levels with normal to elevated LH levels.'''