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Management of Localized Prostate Cancer
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==== <span style="color:#ff0000">Advantages of AS</span> ==== # '''<span style="color:#ff0000">Reduce overdiagnosis/overtreatment of prostate cancer</span>''' #* '''Overdiagnosis refers to a cancer detected by screening that would not be detected during the patient’s lifetime without screening or would never cause disability or death.''' #** There is substantial overdiagnosis of prostate cancer as a result of widespread PSA screening coupled with aggressive biopsy regimens. #** Any screening program will involve detection of some cancers that would not have been otherwise detected. #* '''Overtreatment refers to treatment of men who would otherwise not have known about their cancer in the absence of PSA testing.''' #** The risk of overtreatment of prostate cancer is high when prostate cancer is discovered on prostate biopsies triggered by PSA testing—the most common scenario. '''<span style="color:#ff0000">Disadvantages of AS</span>''' # '''<span style="color:#ff0000">Risk of multiple biopsy procedures</span>''' #* '''Risks of repeat biopsies include infections, erectile dysfunction, complicate subsequent attempts at nerve-sparing surgery''' # '''<span style="color:#ff0000">Delaying treatment and possibly missing the window of opportunity for cure</span>'''
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