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AUA: Upper Tract Urothelial Carcinoma (2023)
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===== Adjuvant intravesical chemotherapy ===== *'''<span style="color:#ff0000">In patients undergoing RNU or SU (including distal ureterectomy) for UTUC, a single dose of perioperative intravesical chemotherapy should be administered in eligible patients to reduce the risk of bladder recurrence.</span>''' **The exact timing of therapy has varied including instilling intravesical chemotherapy at the time of catheter removal (ODMIT-C trial), while other retrospective series reported instillation during surgery or up to 48 hours postoperatively. **Little data to support one intravesical chemotherapeutic over another. ***Many use gemcitabine over mitomycin due to risks of chemical peritonitis with extravesical extravasation of MMC
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