Editing Penile Cancer: Squamous Penile Cancer (section)

==== Summary of treatment strategies for nodal metastases ====
{| class="wikitable"
|'''Lymph node status'''
|'''Management'''
|-
| rowspan="2" |'''No palpable inguinal nodes (cN0)'''
|'''Tis, Ta G1, T1G1: surveillance.'''
|-
|'''> T1G2 [2019 NCCN guidelines: T1b or ≥T2]: invasive lymph node staging by either bilateral modified inguinal lymphadenectomy''' (the medial superficial inguinal lymph nodes and those from the central zone are removed bilaterally, leaving the greater saphenous vein untouched) '''or dynamic sentinel node biopsy'''
|-
|'''Palpable inguinal nodes (cN1/cN2)'''
|'''Palpably enlarged groin lymph nodes should be surgically removed, pathologically assessed (by frozen section) and, if positive, a radical [bilateral?] inguinal lymphadenectomy should be performed'''
|-
|'''Fixed inguinal lymph nodes (cN3)'''
|'''Neoadjuvant chemotherapy followed by radical inguinal lymphadenectomy in responders'''
|-
|'''Pelvic lymph nodes'''
|'''Ipsilateral pelvic lymphadenectomy if ≥2 inguinal nodes are involved on one side or if extracapsular nodal metastasis (pN3) reported.'''
|-
|'''Adjuvant chemotherapy'''
|'''In pN2/pN3 patients after radical lymphadenectomy'''
|-
|'''Radiotherapy'''
|'''Not recommended for nodal disease except as a palliative option'''
|}
'''2018 EAU Penile Cancer Guidelines'''