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CUA: Neurogenic Lower Urinary Tract Dysfunction (2019)
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==== Botox ==== * '''<span style="color:#ff0000">Ona-botulinum toxin A injection (200 units) in the detrusor is an effective, minimally invasive treatment that can achieve continence, improve bladder function, and diminish NDO in individuals with SCI or MS who have an inadequate response to or are intolerant of an anticholinergic medication''' * '''Abo-botulinum toxin A is also effective in NLUTD, with the optimal dose of 750 units''' * Sustained efficacy in terms of reduced incontinence episodes, enhanced bladder function, as well as substantial improvements in key urodynamic parameters and QoL * UTIs and large urine residual or urinary retention are the most frequent adverse events. Therefore, the likelihood of future need of CIC is increased
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