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Microscopic Hematuria (2020 AUA Guidelines)
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=== <span style="color:#ff0000">Risk stratification</span> === * '''<span style="color:#ff0000">Factors to consider (5):</span>''' *# '''<span style="color:#ff0000">Age</span>''' *# '''<span style="color:#ff0000">Smoking</span>''' *# '''<span style="color:#ff0000">Urinalysis</span>''' *# '''<span style="color:#ff0000">Risk factors for urothelial cancer</span>''' *# '''<span style="color:#ff0000">Gross hematuria</span>''' {| class="wikitable" | |'''<span style="color:#ff0000">Low (meets all criteria)''' |'''<span style="color:#ff0000">Intermediate (any of these criteria)''' |'''<span style="color:#ff0000">High (any of these criteria)''' |- |'''Age''' | * Females age <50 years * Males age <40 years | * Females age 50-59 years * Males age 40-59 years | * Females or Males β₯60 years |- |'''Smoking''' |Never smoker OR <10 pack years |10-30 pack years |>30 pack years |- |'''UA''' |3-10 RBC/HPF on a single urinalysis | * 11-25 RBC/HPF on a single urinalysis OR * Low-risk patient with no prior evaluation and 3-10 RBC/HPF on repeat urinalysis |>25 RBC/HPF on a single urinalysis |- |'''Risk factors for urothelial cancer (see below)''' |None |Yes | |- |'''Gross hematuria''' | | |Yes |} * '''<span style="color:#ff0000">Recommended investigations based on risk stratification (4)</span>''' *# '''<span style="color:#ff0000">History and Physical Exam (all patients)</span>''' *# '''<span style="color:#ff0000">Laboratory: serum Cr and GFR (all patients);</span> urine cytology or other markers are not recommended''' *# '''<span style="color:#ff0000">Imaging: upper tract imaging (intermediate, high-risk, and if family history of RCC or other genetic renal tumor syndrome)</span>''' *#* '''<span style="color:#ff0000">US for intermediate-risk</span>''' *#** '''<span style="color:#ff0000">Optional for low-risk</span>''' *#* '''<span style="color:#ff0000">CT urography for high-risk</span>''' *# '''<span style="color:#ff0000">Cystoscopy (intermediate and high-risk)</span>''' *#* '''<span style="color:#ff0000">Optional for low-risk</span>''' **'''<span style="color:#ff0000">Low-risk patients who initially elected not to undergo cystoscopy or upper tract imaging should undergo repeat UA within 6 months'''
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