Editing Peyronie's Disease (2015) (section)

== Diagnosis and Evaluation ==

* '''Mandatory (2):'''
*# '''History''' (to assess penile deformity, interference with intercourse, penile pain, and/or distress)
*# '''Physical exam of the genitalia''' (to assess for palpable abnormalities of the penis)
*** '''Measurement of stretched penile length from the penopubic skin junction to the coronal sulcus or the tip is recommended to establish baseline penile length prior to any intervention.'''
*** '''Plaque(s) can be palpated or documented on ultrasound.'''
**** '''The most common plaque location is on the dorsal mid-shaft'''
* '''Recommended (1):'''
** '''In-office intracavernosal injection (ICI) test with or without duplex Doppler ultrasound should be performed prior to invasive intervention''' (e.g., intralesional treatments, penile prosthesis placement, or surgery)
*** The ICI test enables assessment of penile deformity, plaque(s), and pain in the erect state.
*** When the ICI test is combined with duplex ultrasound, additional measurements of plaque size and/or density can be made, calcified and non-calcified plaques can be differentiated, and information on the vascular integrity of the penis can be obtained.
*** '''Home photography of the erect penis with the use of a protractor during an erection in the office may be sufficient to document deformity from some cases.'''