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Upper Urinary Tract Urothelial Cancer
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===== <span style="color:#ff0000">Risk factors</span> ===== * '''Acquired (see above)'''</span> * <span style="color:#ff0000">'''Hereditary (personal and family history)'''</span> ** <span style="color:#ff0000">'''Identify familial diseases associated with Lynch Syndrome'''</span> ***'''If positive, referral for genetic counseling should be offered.[https://pubmed.ncbi.nlm.nih.gov/37096584/]''' ***'''<span style="color:#ff0000">Lynch syndrome</span>''' ****'''See [[Lynch syndrome|Lynch Syndrome Chapter Notes]]''' ****Familial, autosomal-dominant multi-organ cancer syndrome ****'''Patients undergo routine screening due to increased life-long risk for developing associated malignancies, often occurring before 50 years of age[https://pubmed.ncbi.nlm.nih.gov/37096584/]''' ****May increase the possibility of contralateral upper tract involvement, which is an important potential clinical consideration when developing a treatment plan
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