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Bladder Cancer: Diagnosis and Evaluation
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== Evaluation of Hematuria == === Microscopic hematuria === * '''See [[Microscopic Hematuria (2020 AUA Guidelines)|2020 AUA Microscopic Hematuria Guideline Notes]]''' ** '''Based on risk-stratification into low-, intermediate-, and high-risk''' *** '''History and Physical Exam (all patients)''' *** '''Laboratory: serum Cr and GFR (all patients)''' **** '''Urine cytology or other markers are not recommended''' *** '''Imaging: upper tract imaging (intermediate, high-risk, and if family history of RCC or other genetic renal tumor syndrome)''' **** '''US for intermediate-risk''' **** '''CT urography for high-risk''' *** '''Cystoscopy (intermediate and high-risk)''' === Gross hematuria === *'''No official guidelines''' *'''<span style="color:#ff0000">Evaluation typically includes:</span>''' *# '''<span style="color:#ff0000">History and Physical Exam</span>''' *#'''<span style="color:#ff0000">Laboratory:</span>''' *##'''<span style="color:#ff0000">Urine cytology</span>''' *##'''<span style="color:#ff0000">Serum PSA</span>''' *##* '''Recommended because 10% of patients with recurrent gross hematuria will have prostate cancer''' *#'''<span style="color:#ff0000">Imaging: contrast-enhanced upper tract imaging</span>''' *#* '''<span style="color:#ff0000">For gross hematuria, contrast-enhanced imaging preferred over US</span>'''
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