Editing Management of Localized and Locally Advanced Disease (section)

===== AUA =====
*'''<span style="color:#ff0000">[https://pubmed.ncbi.nlm.nih.gov/28479239/ 2021 AUA Guidelines on Renal Mass and Localized Renal Cancer]</span>'''
** '''<span style="color:#ff0000">Absolute (3):</span>'''
**# '''<span style="color:#ff0000">Anatomic or functionally solitary kidney</span>'''
**# '''<span style="color:#ff0000">Bilateral tumors</span>'''
**# '''<span style="color:#ff0000">Known familial RCC syndrome</span>'''
** '''<span style="color:#ff0000">Relative (4):</span>'''
**# '''<span style="color:#ff0000">cT1a renal masses (preferred over TA and RN)</span>''', not managed with active surveillance
**# '''<span style="color:#ff0000">Pre-existing CKD</span>'''
**# '''<span style="color:#ff0000">Pre-existing proteinuria</span>'''
**# '''<span style="color:#ff0000">Young age</span>'''
**# '''<span style="color:#ff0000">Multifocal masses</span>'''
**# '''<span style="color:#ff0000">Comorbidities that are likely to impact future renal function, including (4):</span>'''
**## '''<span style="color:#ff0000">Moderate to severe hypertension</span>'''
**## '''<span style="color:#ff0000">Diabetes mellitus</span>'''
**## '''<span style="color:#ff0000">Recurrent urolithiasis</span>'''
**## '''<span style="color:#ff0000">Morbid obesity</span>'''