Editing Biochemical Recurrence (section)

== Answers ==

# What is the definition of failure after radical prostatectomy?
#* PSA ≥ 0.2 ng/mL with a second confirmatory laboratory value
# Describe the Pound et al. study which illustrated the natural history of biochemical recurrence after radical prostatectomy
#* Cohort study of 1997 men who underwent radical prostatectomy
#* 15% developed biochemical recurrence
#* The median time from biochemical recurrence to metastasis was 8 years
#* After development of metastatic disease, the median time to death was 5 years
# What is the median PSA in patients with newly detected bone metastasis?
#* 32 ng/mL
# What percentage of patients with biochemical recurrence after radical prostatectomy with PSA <10 ng/mL will have a positive bone scan?
#* 4%
# What is the best study to determine local failure following radical prostatectomy or radiotherapy?
#* MRI
# What is the minimum recommended dose of salvage radiation?
#* 64 Gy