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=== Diabetes === * '''Alibhai et al. JCO 2009''' ** Population: matched cohort study 38,158 males aged 66 or older with prostate cancer ** Comparison: males given continuous ADT for at least 6 months or underwent bilateral orchiectomy vs. those without ** Primary outcomes: acute myocardial infarction, sudden cardiac death, diabetes ** '''Results:''' *** '''Significantly increased risk of incident diabetes''' (hazard ratio 1.16 (95% CI 1.11 - 1.21)) ** Alibhai, Shabbir MH, et al."Impact of androgen deprivation therapy on cardiovascular disease and diabetes." ''Journal of clinical oncology: official journal of the American Society of Clinical Oncology'' 27.21 (2009): 3452.
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