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Stones: Evaluation and Medical Management
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==== <span style="color:#ff0000">Potassium citrate</span> ==== *'''<span style="color:#ff0000">Indications</span>''' **'''<span style="color:#ff0000">Should be offered to patients with (2)</span>''' **#'''<span style="color:#ff0000">Hypocitraturia AND</span>''' **#'''<span style="color:#ff0000">Recurrent calcium or calcium phosphate stones</span>''' **#*'''Citrates are first-line therapy for the management of RTA, thiazide-induced hypocitraturia, and idiopathic hypocitraturia''' **#** Potassium citrate therapy is able to correct the metabolic acidosis and hypokalemia found in patients with distal RTA **#*'''Calcium stone-forming patients with normal citrate excretion but low urinary pH may also benefit from citrate therapy''' **#**There is also a risk that higher urine pH can promote calcium phosphate stone formation, or change calcium oxalate stone formers to calcium phosphate stone formers. **#* '''Potassium citrate is preferred over sodium citrate''' **#**'''Patient's treated with sodium alkali will occasionally begin forming calcium oxalate stones due to an excess sodium load that will inhibit reabsorption of calcium in the proximal tubule, thereby causing hypercalciuria''' **#**'''If the patient is at risk for hyperkalemia, other agents such as sodium bicarbonate or sodium citrate should be considered.''' *'''<span style="color:#ff0000">Adverse Events (2)</span>''' **'''<span style="color:#ff0000">Hyperkalemia</span>''' **'''<span style="color:#ff0000">GI upset</span>'''
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