Editing Peyronie's Disease (section)

== Answers ==

# List risk factors associated with Peyronie’s disease
## Infection
## Trauma
## Diabetes
## Radical prostatectomy
## Autoimmune
## Genetic
## Collagen disorders (Dupuytren’s, plantar fasciitis, tympanosclerosis)
## Aberrant wound healing
# In the absence of treatment, what proportion of patients with Peyronie’s disease will have improvement, no change, or worsening of their disease?
# What is the recommended work-up of a patient with suspected Peyronie’s disease?
#* History, physical exam, detailed examination of erect penis
# What are signs and symptoms associated with Peyronie’s disease?
# What is the differential diagnosis of Peyronie’s Disease?
# Use of which oral medication is supported in the treatment of Peyronie’s disease? Which ones are not recommended? Which ones may be considered?
#* Supported: NSAIDs for pain
#* May be considered: potassium para-aminobenzoate, colchicine, co-enzyme Q10, and/or pentoxifylline
#* Not recommended: vitamin E, tamoxifen, procarbazine, Vitamin E/L-carnitine
# What are the recommended intralesional treatments of Peyronie’s disease? Which are not currently recommended?
#* Recommended: collagenase, interferon alpha, and verapamil
#* Not currently recommended: corticosteroids, botox, PRP
# What are potential adverse events related to the use of intralesional collagenase?
## Penile hematoma
## Pain
## Swelling
## Corporal rupture
# Which Peyronie’s disease defects may not be suitable for intralesional collagenase?
# What is the role of extracorporeal shockwave lithotripsy in the management of Peyronie’s disease? Penile traction? Radiotherapy?
# What are the indications for surgery of Peyronie’s disease?
## Stable disease (defined as disease that is ≥ 1 year from onset and ≥6 months of stable deformity)
## Deformity that compromises sexual intercourse
## Failure of conservative therapy
## Desire for most rapid and reliable result
# What are potential risks of surgical intervention for Peyronie’s disease?
## Persistent or recurrent curvature
## Loss of penile length
## Loss of penile sensation
## Reduced erectile rigidity
# What are the surgical options to treat Peyronie’s disease? Which approach is suitable for a patient with intact erectile function and an hourglass deformity?
# What are different techniques of performing tunical plication?