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Biochemical Recurrence
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=== Epidemiology === * '''Incidence: β25-41% develop PSA recurrence within 10 years of radical prostatectomy''' ** '''In patients that have BCR after radical prostatectomy''' *** β50% of recurrences appear within 3 years *** β80% within 5 years *** '''β99% within 10 years''' *** Rarely, BCR can occur > 15 years after radical prostatectomy *** '''Clinical implication: given low risk of recurrence after 10 years and protracted course of untreated biochemical recurrence (see Pound et al. below), likely low utility of PSA follow-up beyond 10 years, particularly in older patient (average life expectancy of US male in 2018: 78.5)'''
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