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Bladder Cancer: Pathology
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=== CIS === * A flat, non-invasive urothelial carcinoma * '''HG by definition and is regarded as a precursor to the development of invasive HG cancer''' ** '''<span style="color:#ff0000">Lesions interpreted as severe dysplasia or severe atypia are regarded as being the same entity as CIS</span>''' * Rarely found in isolation; majority (90%) found in association with papillary or nodular bladder tumours * Considered a field disease, as it can affect multiple areas in the bladder, the upper urinary tract, and the urethra * Classified as ** Primary: no previous history of bladder cancer (best prognosis) ** Secondary: new lesion diagnosed during follow-up
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