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CUA: Male LUTS & BPH (2018)
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===== '''UrologySchool.com summary of size considerations:''' ===== * '''TURP: 30-80g''' * '''Plasma button: <60g''' * '''Open simple: >80g''' * '''TUIP: <30g''' * '''Urolift, aquablation: <80g''' ** Urolift cannot be done with median lobe, aquablation can * '''HOLEP/PVP: not explicitly stated''' * Ejaculatory preserving: TUIP, urolift, aquablation ** '''TURP''' *** '''Monopolar TURP (M-TURP)''' **** '''Standard first-line surgical therapy for men with moderate to severe MLUTS/BPH with prostate volume of 30β80 cc''' **** '''Potential complications:''' bleeding (2β9%), capsule perforation with significant extravasation (2%), TUR syndrome (0.8%), urinary retention (4.5β13%), infection (3β4%; sepsis 1.5%), incontinence (<1%), bladder neck contracture (3β5%), retrograde ejaculation (65%), erectile dysfunction (6.5%), and surgical retreatment (2%/year). *** '''Bipolar TURP (B-TURP)''' **** '''Standard first-line surgical therapy for men with moderate to severe MLUTS/BPH with prostate volume of 30β80 cc;''' has evolved as an equivalent alternative to the monopolar technique **** '''Advantages (3):''' ****# '''Reduction in the risk of dilutional hyponatremia (TUR syndrome)''' ****# '''Improvements in intraoperative visibility''' ****# '''May result in shorter catheterization times''' *** '''Bipolar plasma kinetic vaporization/plasma button TURP''' **** '''An alternative first-line surgical therapy for men with moderate to severe MLUTS/BPH and prostate volume <60 cc''' ** '''Open simple prostatectomy''' *** '''First-line surgical therapy for men with moderate to severe MLUTS/BPH and prostate volume >80 cc''' *** '''Other indications for OSP include (2):''' ***# '''Plans for concurrent bladder procedure, such as diverticulectomy or cystolithotomy''' ***# '''Men who are unable to be placed in dorsal lithotomy position due to severe hip disease''' ** '''Laser prostatectomy''' *** '''Can be used to treat men on anti-coagulation and those with bleeding dyscrasia''' *** '''Holmium laser enucleation of the prostate (HoLEP)''' **** The procedure requires a steep learning curve (estimated >20β50 cases) often requiring fellowship training. **** '''We recommend HoLEP as an alternative to TURP or OSP in men with moderate to severe LUTS if performed by a HoLEP-trained surgeon [no size cut-off]''' *** '''Photoselective vaporization of the prostate (PVP)''' **** '''We recommend PVP as an alternative to TURP in men with moderate to severe LUTS [no size cut-off]''' **** '''We suggest Greenlight PVP therapy as an alternate surgical approach in men on anti-coagulation''' or with a high cardiovascular risk *** '''Diode laser vaporization of the prostate''' **** '''We suggest diode laser vaporization of the prostate as an alternative to TURP in men with moderate to severe LUTS''' **** We suggest diode laser vaporization of the prostate as an alternate surgical approach in men on antic-oagulation *** '''Thulium laser''' **** '''We suggest Tm:YAG vaporization of the prostate as an alternative to TURP in men with moderate to severe LUTS with prostate volume <60 cc.''' **** '''Thulium enucleation may be an alternative to OSP and HoLEP in men with moderate to severe LUTS with prostate volume >80 cc''' ** '''Transurethral incision of the prostate (TUIP)''' *** '''We recommend TUIP to treat moderate to severe LUTS in men with prostate volume <30 cc without a middle lobe.''' '''These patients should experience symptom improvements similar to TURP with a lower incidence of retrograde ejaculation.''' ** '''Minimally invasive surgical therapies''' *** '''Transurethral microwave therapy (TUMT): an option for elderly patients with significant comorbidities or greater anaesthesia risks as long-term durability is limited''' *** '''Transurethral needle ablation (TUNA): should not be offered as a consideration for treatment of BPH/LUTS''' *** '''Prostatic stents should only be used as an alternative to catheterization in men unfit for surgery with a functional detrusor for those medically unfit for surgery''' ** '''New and emerging therapies''' *** '''Prostatic urethral lift (Urolift):''' **** '''Provides less effective, but adequate and durable improvements in IPSS and Qmax compared to TURP''' **** '''Preserves sexual function, no reported case of retrograde ejaculation'''. **** '''May be considered an alternative treatment for men with LUTS interested in preserving ejaculatory function, with prostates <80 cc and no middle lobe''' *** '''Rezum system of convective water vapour energy ablation:''' **** '''May be considered an alternative treatment for men with LUTS interested in preserving ejaculatory function, with prostates <80 cc, with or without middle lobe''' *** '''Image-guided robotic waterjet ablation:''' **** '''Offered to men with LUTS interested in preserving ejaculatory function, with prostates <80 cc, with or without middle lobe''' *** '''Temporary implantable nitinol device (iTIND):''' We recommend that iTIND (a mechanical, stent-like device designed to remodel the bladder neck and the prostatic urethra through pressure necrosis) '''should not be offered at this time for the treatment of LUTS due to BPH''' *** '''Prostatic artery embolization (PAE): should not be offered at this time for the treatment of LUTS due to BPH'''
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