Editing Hypercortisolism (section)

=== History and Physical Exam ===

* See Campbell's 11th edition Table 65-2 for Primary Effects of Glucocorticoids
* '''Classic symptoms of hypercortisolism, such as central obesity, moon facies, buffalo hump, facial plethora, menstrual disturbances, hirsuitism, proximal muscle weakness, easy bruisability, and abdominal striae, are nonspecific.'''
* '''Cushing syndrome also results in systemic symptomatology, such as dyslipidemia, insulin resistance, and hypertension, similar to the highly-prevalent metabolic syndrome'''

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* '''Urological complications of Cushing's syndrome'''

# '''Erectile dysfunction''', decreased libido
# '''Hypogonadal hypogonadism'''
#* '''Relatively common in men with Cushing syndrome'''
#* '''Consider initiating a hypercortisolism workup in men with libido or erectile problems, low testosterone, and low gonadotropin levels'''
# '''Urolithiasis'''
#* '''Up to 50% of patients with Cushing syndrome exhibit urolithiasis'''
#* Stone formers with cushingoid features also should receive a hypercortisolemia evaluation