Editing Radiotherapy for Prostate Cancer (section)

== Molecular Therapies and Radiation for Prostate Cancer ==

* Targeted RNA-Based Therapy
** Chemical or short-interfering RNA (siRNA) inhibition of DNA repair proteins, such as DNA-dependent protein kinase ATM, results in cellular hypersensitivity to irradiation. Although these approaches have potential, they lack a means to selectively target cancer cells to avoid sensitization of surrounding non-cancerous tissues.
** RNA interference (RNAi) is a promising new therapeutic approach, but the challenge for translating RNAi therapy is delivery, particularly for specific cell types.