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Prostate Cancer: Diagnosis and evaluation
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====== NCCN ====== *'''NCCN (version 2.2021)''' ** '''<span style="color:#ff0000">Recommended (5):''' **# '''<span style="color:#ff0000">Ashkenazi Jewish ancestry''' **#'''<span style="color:#ff0000">Positive family history of high-risk germline mutations (e.g. BRCA 1/2, Lynch syndrome)''' **#* '''BRCA-cancers (5): breast, ovarian, pancreatic, prostate, melanoma''' **#* '''Lynch syndrome cancers: (8) colonic (most common), endometrial (second most common), prostate, urothelial, adrenal, gastric, pancreatic, uterine, ovarian, and sebaceous carcinomas''' **#'''<span style="color:#ff0000">Personal history of breast cancer''' **#'''<span style="color:#ff0000">Metastatic (distant or regional (node-positive) prostate cancer''' **# '''<span style="color:#ff0000">High- or very-high risk localized prostate cancer''' ** '''Optional (2)''' **# '''Intermediate-risk with intraductal or cribiform histology''' **# '''Personal history of colorectal, gastric, melanoma, upper tract urothelial, glioblastoma, biliary tract, or small intestine'''
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