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====== Outcomes ====== * '''Predominantly SUI''' **'''No risk factors that consistently predict outcomes''' ** '''<span style="color:#ff0000">PVS are particularly helpful in treating ISD (in contrast to midurethral sling)''' ** '''The reported cure rate of PVS surgery for recurrent SUI is excellent''' ** '''Autologous PVS''' *** '''Continence rate after PVS ranges from 61-97%'''; wide range due to variation in outcome definition *** Postoperative de novo or urgency incontinence rates range from 2-21% **** '''Most common reason for failure/patient dissatisfaction relates to urgency symptoms and urgency incontinence at follow-up''' ** '''Allograft PVS''' *** Limited outcome data, and the '''efficacy and durability of these slings are questionable''' *** Previously reported failures coupled with the consistent success and rapid adoption of synthetic MUSs has led to abandonment of all types of cadaveric allograft at most centers. ** '''Xenograft PVS''' *** Because of the morbidity of autologous fascial harvest, high failure rates of allograft materials, and high exposure and perforation rates with synthetic PVSs, xenografts are an attractive option. *** In general, they are associated with a low rate of infection, exposure, and perforation owing to their incorporation into host tissue cure rates comparable to those of the autologous sling. *** '''In RCTs, porcine dermis was associated with significantly inferior long-term cure rates compared with the autologous PVS''' * '''Autologous PVS for Mixed Urinary Incontinence''' ** '''Overall, PVS remains an effective treatment option for MUI with cure rates similar to those of simple SUI.''' *** '''The treatment of patients with mixed urgency and SUI is complicated and often involves a combination of anticholinergic therapy and surgery''' *** PVS is an effective treatment option for stress-induced DO with cure rates similar to those of simple DO. *** '''Anti-incontinence surgery may cure or aggravate urgency symptoms or lead to de novo urgency. This aspect of anti-incontinence surgery is unpredictable and a major cause of patient dissatisfaction''' *** '''The presence of residual urgency is similar to de novo urgency with a PVS.''' * '''Autologous PVS for Urethral Reconstruction''' ** '''<span style="color:#ff0000">Autologous PVSs in the setting of urethral reconstruction (urethral fistula, urethral diverticulum, destroyed urethra) has excellent results when compared with other surgeries for incontinence'''
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