Editing Functional: Pharmacological Management of LUTS (section)

=== Decreasing Outlet Resistance at the Level of the Striated Sphincter ===
* '''No class of pharmacologic agents that will selectively relax the striated musculature of the pelvic floor.''' 
*'''Injection of botulinum toxin into the striated sphincter has been used with some clinical success, especially in patients with neurologic striated sphincter dyssynergia'''. 
**The potential for spread to nearby structures is greater than with intravesical therapy, and distant effects can also occur, but these are rare