Editing Hormonal Therapy (section)

=== Cardiometabolic ===

* '''Lifestyle changes (smoking cessation, dietary modifications, exercise)'''
** Patients should be encouraged to attend supervised exercise programs using a combination of resistance and aerobic training
*** Supervised exercise therapy in men with PCa is superior to self-implemented exercise regimens
*** '''Benefits of exercise in males on ADT (10)'''
**** '''Physical domains (5):'''
****# '''Prevention of muscle loss and resultant decline in lean body mass'''
****# '''Decreased body mass index'''
****# '''Improved muscle strength'''
****# '''Improvements in peak oxygen consumption and endothelial function'''
****# '''Improved overall physical function'''
**** '''Functional domains (2):'''
****# '''Lower levels of fatigue'''
****# '''Decreased risk of falls and fractures'''
**** '''Endocrine domains (2):'''
****# '''Improved insulin and glucose homeostasis'''
****# '''Improved in lipid profile'''
**** '''Multiple health-related quality of life domains'''
* '''Monitor blood pressure and treat hypertension''' for a target of <130/80
* '''Diabetes screening and lipid profile (see above) assessments should be continued at 6–12 month-intervals throughout treatment duration'''
** Dyslipidemia should be treated according to current best practice guidelines