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AUA: Upper Tract Urothelial Carcinoma (2023)
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=== Imaging === * '''<span style="color:#ff0000">Cross-sectional imaging of the upper tract with contrast including delayed images</span>''' ** '''<span style="color:#ff0000">Preferred modality: multiphase computed tomography (CT) scan with excretory phase imaging of the urothelium</span>''' *** Pooled sensitivity of 92% *** Pooled specificity of 95% ** '''<span style="color:#ff0000">If contraindications to contrast-enhanced CT such as chronic kidney disease (CKD) (e.g. eGFR <30[https://medicine.yale.edu/diagnosticradiology/patientcare/policies/nephropathy/]) or untreatable allergy to iodinated contrast medium, use magnetic resonance (MR) urography</span>''' *** MRI is less sensitive than CT, similar specificity ** '''If contraindications to multiphasic CT and MR urography, use retrograde pyelography in conjunction with non-contrast axial imaging (renal ultrasound) to assess the upper urinary tracts.''' *PET scans **Should not be obtained routinely **May be selectively considered for patients who are at risk for metastatic recurrence and are not able to have contrast enhanced CT and MRI *Patients with findings suggestive of metastatic UTUC should be evaluated to define the extent of disease and referred to medical oncology for further management
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